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Hryhorczuk C, Sheng Z, Décarie-Spain L, Giguère N, Ducrot C, Trudeau L-E, Routh V, Alquier T, Fulton S (2017) Oleic acid in the ventral tegmental area inhibits feeding, food reward and dopamine tone. Neuropsychopharmacology (in press).

Lussier F, Brule T, Bourque MJ, Ducrot C, Trudeau L-E, Masson J-F (2017) Dynamic SERS nanosensor for neurotransmitters sensing near neurons. Faraday Discussions (in press).

Gleave JA, Arathoon LR, Trinh D, Lizal KE, Giguère N, Barber JHM, Najarali Z, Khan MH, Thiele SL, Semmen MS, Koprich JB, Brotchie JM, Eubanks JH, Trudeau L-E, Nash JE (2017) Sirtuin 3 rescues neurons through the stabilisation of mitochondrial biogenetics in the virally-expressing mutant α-synuclein rat model of parkinsonism. Neurobiology of Disease 106:133-146.

Ramet L, Zimmermann J, Bersot T, Poirel O, De Gois S, Silm K, Sakae DY, Mansouri-Guilani N, Bourque MJ, Trudeau L-E, Pietrancosta N, Daumas S, Bernard V, Rosenmund C, El Mestikawy S. (2017) Characterization of a Human Point Mutation of VGLUT3 (p.A211V) in the Rodent Brain Suggests a Nonuniform Distribution of the Transporter in Synaptic Vesicles. Journal of Neuroscience 37(15):4181-4199.

Doucet-Beaupré H, Gilbert C, Profes MS, Chabrat A, Pacelli C, Giguère N, Rioux V, Charest J, Deng Q, Laguna A, Ericson J, Perlmann T, Ang SL, Cicchetti F, Parent M, Trudeau L-E, Lévesque M. (2016) Lmx1a and Lmx1b regulate mitochondrial functions and survival of adult midbrain dopaminergic neurons. Proc Natl Acad Sci U S A 113(30):E4387-96. Paper in PDF format.

Matheoud D, Sugiura A, Bellemare-Pelletier A, Laplante A, Rondeau C, Chemali M, Fazel A, Bergeron JJ, Trudeau L-E, Burelle Y, Gagnon E, McBride HM, Desjardins M. (2016) Parkinson's Disease-Related Proteins PINK1 and Parkin Repress Mitochondrial Antigen Presentation. Cell 166(2):314-27. Paper in PDF format.

Voisin AN, Mnie-Filali O, Giguère N, Fortin GM, Vigneault E, El Mestikawy S, Descarries L, Trudeau LÉ. (2016) Axonal Segregation and Role of the Vesicular Glutamate Transporter VGLUT3 in Serotonin Neurons. Frontiers in Neuroanatomy 10:39. Paper in PDF format.

Giguère N, Trudeau LÉ. (2016) Axon arborization size is a key factor influencing cellular bioenergetics and vulnerability of dopamine neurons in Parkinson's disease. Médecine Science (Paris). 32(4):342-4. Paper in PDF format.

Selleri S, Bifsha P, Civini S, Pacelli C, Dieng MM, Lemieux W, Jin P, Bazin R, Patey N, Marincola FM, Moldovan F, Zaouter C, Trudeau L-E, Benabdhalla B, Louis I, Beauséjour C, Stroncek D, Le Deist F, Haddad E. (2016) Human mesenchymal stromal cell-secreted lactate induces M2-macrophage differentiation by metabolic reprogramming. Oncotarget 7(21):30193-210. Paper in PDF format.

Samuel F, Flavin WP, Iqbal S, Pacelli C, Sri Renganathan SD, Trudeau L-É, Campbell EM, Fraser PE, Tandon A. (2016) Effects of Serine 129 Phosphorylation on α-Synuclein Aggregation, Membrane Association, and Internalization. Journal of Biological Chemistry 291(9):4374-85. Paper in PDF format.

Ng E, Varaschin RK, Su P, Browne CJ, Hermainski J, Le Foll B, Pongs O, Liu F, Trudeau L-É, Roder JC, Wong AHC. (2016) Neuronal calcium sensor-1 deletion in the mouse decreases motivation and dopamine release in the nucleus accumbens. Behavioral Brain Research 301: 213-225. Paper in PDF format.

Pacelli C, Giguère N, Bourque MJ, Lévesque M, Slack RS, Trudeau L-É. (2015) Elevated Mitochondrial Bioenergetics and Axonal Arborization Size Are Key Contributors to the Vulnerability of Dopamine Neurons. Current Biology 25(18):2349-60. Paper in PDF format.

Apuschkin M, Stilling S, Rahbek-Clemmensen T, Sørensen G, Fortin G, Herborg Hansen F, Eriksen J, Trudeau L-E, Egerod K, Gether U, Rickhag M (2015) A novel dopamine transporter transgenic mouse line for identification and purification of midbrain dopaminergic neurons reveals midbrain heterogeneity. Eur J Neurosci 42(7):2438-54. Paper in PDF format.

Thibault D, Giguère N, Loustalot F, Bourque M-J, Ducrot C, El Mestikawy S, Trudeau LE (2015) Homeostatic regulation of excitatory synapses on striatal medium spiny neurons expressing the D2 dopamine receptor. Brain Structure & Function 221(4):2093-107. Paper in PDF format.

Trudeau L-E, Hnasko TS, Wallén-Mackenzie A, Morales M, Rayport S, Sulzer D (2014) The multilingual nature of dopamine neurons. Prog. Brain Res. 211: 141-164. Paper in PDF format.

Sanchez G., Varaschin RK, Bueler H, Marcogliese PC, Park DS, Trudeau L-E(2014) Unimpaired striatal dopamine release in juvenile Parkin knockout, Pink1 knockout, DJ-1 knockout and LRRK2 R1441G transgenic mice PloS One 9(4): e94826. Paper in PDF format.

Charfi I, Nagi K, Mnie-Filali O, Thibault D, Balboni G, Schiller PW, Trudeau L-E, Pineyro G (2014) Ligand and cell-dependent determinants of internalization and cAMP modulation by delta opioid receptor (DOR) agonists. Cell. Mol. Life Sci.71(8):1529-46. Paper in PDF format.

Poliquin PO, Chen J, Cloutier M, Trudeau L-E, Jolicoeur M (2013) Metabolomics and in-silico analysis reveal critical energy deregulations in animal models of Parkinson’s disease. PLoS One, 8(7): e69146. Paper in PDF format.

Thibault D, Loustalot F, Fortin GM, Bourque MJ, Trudeau L-E (2013) Evaluation of D1 and D2 dopamine receptor segregation in the developing striatum using BAC transgenic mice. PLoS One, 8(7): e67219. Paper in PDF format.

Fasano C, Bourque MJ, Lapointe G, Leo D, Haber M, Kortleven C, Desgroseillers L, Murai K, Trudeau L-E (2013) Dopamine facilitates dendritic spine formation by cultured striatal medium spiny neurons through both D1 and D2 dopamine receptors. Neuropharmacology 67:432-443. Paper in PDF format.

Hernandez-Blatazar D, Martinez-Fong D, Trudeau L-E (2012) Optimizing NTS-Polyplex as a tool for gene transfer to cultured dopamine neurons. PLOS One7(12): e51341. Paper in PDF format.

 Fortin GM, Bourque MJ, Mendez JA, Leo D, Nordenankar K, Birgner C, Arvidsson E, Rymar VV, Bérubé-Carière N, Claveau AN, Descarries L, Sadikot AF, Wallen-Mackenzie A, Trudeau L-E. (2012) Glutamate corelease promotes growth and survival of midbrain dopamine neurons. Journal of Neuroscience, 32(48) : 17447-17492. Paper in PDF format.

Kortleven C, Bruneau LC, Trudeau L-E. (2012) Neurotensin inhibits glutamate-mediated synaptic inputs onto ventral tegmental area dopamine neurons through the release of the endocannabinoid 2-AG. Neuropharmacology, 63(6):983-91. Paper in PDF format.

Martinez-Fong D, Bannon MJ, Trudeau L-E, Gonzalez-Barrios JA, Arango-Rodriguez ML, Hernandez-Chan NG, Reyes-Corona D, Armendáriz-Borunda J Navarro-Quiroga I (2012) NTS-polyplex: A potential nanocarrier for neurotrophic therapy of Parkinson’s disease. Nanomedicine: Nanotechnology, Biology, and Medicine, 8(7):1052-69. Paper in PDF format.

Bérubé-Carrière N, Guay G, Fortin GM, Kullander K, Olson L, Wallen-Mackenzie A, Trudeau, L-E, Descarries L. (2012) Ultrastructural characterization of the mesostriatal dopamine innervation in mice, including two mouse lines of conditional VGLUT2 knockout in dopamine neurons. European Journal of Neuroscience, 35(4):527-538. Paper in PDF format.

Alsiö J, Nordenankar K, Arvidsson E, Birgner C, Mahmoudi S, Halbout B, Smith C, Fortin GM, Olson L, Descarries L, Trudeau LE, Kullander K, Lévesque D, Wallén-Mackenzie A. (2011) Enhanced Sucrose and Cocaine Self-Administration and Cue-Induced Drug Seeking after Loss of VGLUT2 in Midbrain Dopamine Neurons in Mice. Journal of Neuroscience 31(35):12593-12603. Paper in PDF format.

Martel P, Leo D, Fulton S, Bérard M, Trudeau LE. (2011) Role of kv1 potassium channels in regulating dopamine release and presynaptic d2 receptor function. PLoS One. 6(5):e20402. Paper in PDF format.

El Mestikawy, S., Wallen-Mackenzie, A., Fortin, G., Descarries, L., Trudeau, L.-E. (2011) From glutamate corelease to vesicular synergy: new perspectives on the functions of vesicular glutamate transporters. Nature Reviews Neuroscience 12(4):204-16. Paper in PDF format.

Kortleven C, Fasano C, Kortleven C, Lacaille JC and Trudeau, L-E (2011)  The endocannabinoid 2-Arachidonoylglycerol inhibits long-term potentiation of glutamatergic synapses onto ventral tegmental area dopamine neurons in mice. European Journal of Neuroscience 33(10):1751-60. Paper in PDF format.

Fulton, S, Thibault., D., Mendez, J.A., Lahaie, N., Tirotta, E., Borrelli, E., Bouvier, M., Tempel, B, Trudeau, L.-E. (2011) Contribution of Kv1.1 and 1.2 voltage-gated potassium channels to D2 autoreceptor regulation of axonal dopamine overflow. Journal of Biological Chemistry 286(11):9360-72. Paper in PDF format.

Thibault D, Albert, PR, Pineyro G and Trudeau L-E (2011) Neurotensin triggers D2 dopamine receptor desensitization through a PKC and beta-arrestin1-dependent mechanism. Journal of Biological Chemistry 286(11):9174-84.Paper in PDF format.

Drouin-Ouellet J, Brownell AL, Saint-Pierre M, Fasano C, Vincent E, Trudeau L-E, Lévesque D, Cicchetti F (2010) Neuroinflammation is associated with changes in glial mGluR5 expression and the development of neonatal excitotoxic lesions. Glia 59(2):188-99. Paper in PDF format.

Fasano, C., Kortleven, C., Trudeau, L.-E. (2010) Chronic activation of the D2 autoreceptor inhibits both glutamate and dopamine synapse formation and alters the intrinsic properties of mesencephalic dopamine neurons in vitro. European Journal of Neuroscience 32(9):1433-41. Paper in PDF format

Xu, B., Goldman. J.S., Rymar, V.V., Forget, C., Lo, P.S., Bull, S.-J., Vereker, E., Barker, P.A., Trudeau, L.-E., Sadikot, A.F., Kennedy, T.E. (2010) Critical Roles for the Netrin Receptor DCC in Dopaminergic Neuronal Precursor Migration, Axon Guidance, and Axon Arborization. Neuroscience 169(2):932-949. Paper in PDF format

Birgner C, Nordenankar K, Lundblad M, Mendez JA, Smith C, le Grevès M, Galter D, Olson L, Fredriksson A, Trudeau L.-E, Kullander K, Wallén-Mackenzie A. (2010) VGLUT2 in dopamine neurons is required for psychostimulant-induced behavioral activation. Proc Natl Acad Sci U S A. 107(1):389-94. Paper in PDF format.

Thibault, D., Kortleven, C., Fasano, C., Dal Bo, G., Trudeau, L.-E. (2010) Découvertes récentes sur la fonction et la plasticité des voies dopaminergiques du cerveau. Médecine/Sciences 26 : 165-170. Paper in PDF format.

Bérubé-Carrière, N., Riad, M., Dal Bo G., Lévesque, D., Trudeau, L.-E., Descarries, L. (2009) The dual dopamine-glutamate phenotype of growing mesencephalic neurons regresses in mature rat brain. J. Comp. Neurol.517(6):873-91. Paper in PDF format.

Fawaz, C.S., Martel, P., Leo, D., Trudeau, L.-E. (2009) Presynaptic action of neurotensin on dopamine release through inhibition of D2 receptor function.BMC Neuroscience 10(1): 96 (open access article). Paper in PDF format.

Trudeau, L.-E., Dal Bo, G., Mendez, J. A. (2009) Glutamate co-release by monoamine neurons. In Co-existence and co-release of classical neurotransmitters. Gutierrez R (Ed), Springer, New York, pp. 127-144.

Descarries, L., Bérubé-Carrière, N., Riad, M., Dal Bo, G., Mendez, J.A. Trudeau, L.-É. (2008) Glutamate in dopamine neurons: synaptic versus diffuse transmission. In: Communication and Integration in the Basal Ganglia, K. Fuxe, L.F. Agnati, F. Mora and R. Schwarcz Eds. Brain Res. Rev. 58: 290-302. Paper in PDF format.

Fasano, C., Poirier, A., Desgroseillers, L., Trudeau, L.-E. (2008) Chronic activation of the D2 dopamine autoreceptor inhibits synaptogenesis in mesencephalic dopaminergic neurons in vitro. Eur. J. Neurosci. 28: 1480-1490. Paper in PDF format.

Sulzer D, Trudeau L.-E, Rayport S (2008) Postnatally derived ventral midbrain dopamine neuron cultures as a model system for studying neurotoxicity and Parkinson’s disease. In Parkinson’s Disease: Molecular and Therapeutic Insights from Model Systems. Nass R (Ed), Academic Press, Burlington, MA, pp. 491-504.

Dal Bo, G., Bérubé-Carrières, N., Mendez, J.A., Riad, M., Descarries, L., Lévesque, D., Trudeau, L.-E. (2008) The glutamatergic phenotype of mesencephalic dopamine neurons is enhanced following a neonatal 6-hydroxydopamine lesion. Neuroscience, 156(1): 59-70. Paper in PDF format.

Mendez JA, Bourque MJ, Dal Bo G, Bourdeau ML, Danik M, Williams S, Lacaille JC, Trudeau L-E (2008) Developmental and target-dependent regulation of vesicular glutamate transporter expression by dopamine neurons. Journal of Neuroscience 28(25):6309-6318. Paper in PDF format.

Fasano C, Thibault D, Trudeau L-E (2008) Culture of postnatal mesencephalic dopamine neurons on an astrocyte monolayer. Current Protocols in Neuroscience  July; Chapter 3:Unit 3.21

Huh CY, Danik M, Manseau F, Trudeau L-E, Williams S. (2008) Chronic exposure to nerve growth factor increases acetylcholine and glutamate release from cholinergic neurons of the rat medial septum and diagonal band of Broca via mechanisms mediated by p75NTR. Journal of Neuroscience 6;28(6):1404-9. Paper in PDF format.

Descarries, L., Bérubé-Carrière, N., Riad, M., Dal Bo, G., Mendez, J.A., Trudeau, L.-E. (2008) Glutamate in dopamine neurons : synaptic versus diffuse transmission. Brain Research Reviews 58(2): 290-302. Article en format PDF.

Trudeau, L.-E (2007) Antipsychotiques, dopamine et glutamate, une relation à établir. Santé Mentale au Québec 32: 191-199. Article in PDF format.

Trudeau, L.-E. & Gutierrez, R. (2007) On cotransmission and neurotransmitter phenotype plasticity. Molecular Interventions 7(3) : 138-146. Paper in PDF format.

Jomphe, C., Lemelin, P.-L., Okano, H., Kobayashi, K. & Trudeau, L.-E. (2006)  Bidirectional regulation of dopamine D2 and neurotensin NTS1 receptors in dopamine neurons. European Journal of Neuroscience 24(10): 2789-2800.Paper in PDF format.

Forget, C., Stewart, J. & Trudeau, L.-E. (2006) Impact of basic FGF expression in astrocytes on dopamine neuron synaptic function and development. European Journal of Neuroscience 23: 608-616. Paper in PDF format

St-Gelais, F., Jomphe, C. & Trudeau, L.-E. (2006) Role of neurotensin in CNS pathophysiology: what is the evidence? Journal of Psychiatry and
Neuroscience
 31: 229-245. Paper in PDF format

Gonzalez-Barrios, J.A., Lindahl, M, Bannon, M.J., Anaya-Martınez, V, Flores, G. Navarro-Quiroga,I,  Trudeau, L.-E., Aceves, J., Martinez-Arguelles, D.B., Garcia-Villegas, R., Jimenez,I., Segovia, J. & Martinez-Fong, D. (2006). Neurotensin polyplex as an efficient carrier for delivering the human GDNF gene into nigral dopamine neurons of hemiparkinsonian rats. Molecular Therapy 14(6): 857-865. Paper in PDF format.

Jomphe, C., Tiberi, M. & Trudeau, L.-E. (2006) Expression of D2 receptor isoforms in cultured neurons reveals equipotent autoreceptor function. Neuropharmacology 50: 595-605. Paper in PDF format

Fortin, G.D., Desrosiers, C.C., Yamaguchi, N., & Trudeau, L.-E. (2006) Basal somatodendritic dopamine release requires SNARE proteins. Journal of Neurochemistry 96: 1740-1749. Paper in PDF format

Croft, B.G., Fortin, G., Corera, A.T., Edwards, R.H. , Beaudet, A., Trudeau, L.-E.& Fon, E.A. (2005) Normal Biogenesis and Cycling of Synaptic Vesicles in Dopamine Neurons of Vesicular Monoamine Transporter 2 Knockout Mice. Molecular Biology of the Cell 16: 306-315. Paper in PDF format

Michel, F.J., Fortin, G., Martel, P., Yeomans, J & Trudeau, L.-E. (2005) M3-muscarinic receptors mediate Ca2+ influx in rat mesencephalic GABAergic neurones through a protein kinase C-dependent mechanism. Neuropharmacology 48(6): 796-809. Paper in PDF format

Drapeau, J., El-Helou, V., Clement, R., Bel-Hadj, S., Gosselin, H., Trudeau L.-E., Villeneuve, L. & Calderone, A. (2005) Nestin-expressing neural stem cells identified in the scar following myocardial infarction. J Cell Physiol. 204: 51-62. Paper in PDF format

Jomphe, C., Bourque, M.J., Fortin, G., St-Gelais, F., Okano, H., Kobayashi, K. & Trudeau, L.-E. (2005) Use of TH-GFP transgenic mice as a source of identified dopaminergic neurons for physiological studies in postnatal cell culture. Journal of Neuroscience Methods 146: 1-12. Paper in PDF format

Dal Bo, G., St-Gelais, F., Danik, M., Williams, S., Cotton, M. & Trudeau, L.-E. (2004) Dopamine neurons in culture express VGLUT2 explaining their capacity to release glutamate at synapses in addition to dopamine. Journal of Neurochemistry 88: 1398-1405. Paper in PDF format

St-Gelais, F., Legault, M., Rompré, P.-P. & Trudeau, L.-E. (2004) Role of calcium in neurotensin-evoked enhancement in firing in mesencephalic dopamine neurons. Journal of Neuroscience 24: 2566-2574. Paper in PDF format

Michel, F.J., Robillard, J.M. & Trudeau, L.-E. (2004) Regulation of rat mesencephalic GABAergic neurons through muscarinic receptors. Journal of Physiology 556(2): 429-445. Paper in PDF format

St-Gelais, F., Ménard, C., Congar, P., Trudeau, L.-E. & Massicotte, G. (2004) Postsynaptic injection of calcium-independent phospholipase A2 inhibitors selectively increases AMPA receptor-mediated synaptic transmission. Hippocampus 14: 319-325. Paper in PDF format

Trudeau, L.-E. (2004) Glutamate co-transmission as an emerging concept in monoamine neuron function. Journal of Psychiatry and Neuroscience 29: 296-310. Paper in PDF format

Jomphe, C, Lévesque, D & Trudeau, L.-E. (2003) Calcium-dependent, D2 receptor-independent induction of c-fos by haloperidol in cultured dopamine neurons. Naunyn-Schmiedeberg’s Archives of Pharmacology 367: 480-489. Paper in PDF format

Congar, P., Bergevin, A & Trudeau, L.-E. (2002) D2 Receptors Inhibit the Secretory Process Downstream From Calcium Influx in Dopaminergic Neurons: Implication of K+ Channels. Journal of Neurophysiology 87:1046-1056. Paper in PDF format

Legault, M., Congar, P., Michel, F.J. & Trudeau, L.-E. (2002) Presynaptic action of neurotensin on cultured ventral tegmental area dopaminergic neurones. Neuroscience 111:177-187. Paper in PDF format

Galarneau, A, Primeau, M., Trudeau, L.-E. & Michnick, S.W. (2002) Beta-Lactamase Protein fragment Complementation Assays as in vivo and in vitro Sensors of Protein-Protein Interactions. Nature Biotechnology 20:619-622. Paper in PDF format

Bergevin, A., Girardot, D. Bourque, M.-J. & Trudeau, L.-E. (2002) Presynaptic µ-opioid Receptors Regulate a Late Step of the Secretory Process in Rat Ventral Tegmental Area GABAergic Neurons. Neuropharmacology 42:1065-1078. Paper in PDF format

Congar, P. & Trudeau, L.-E. (2002) Perturbation of synaptic vesicle delivery during neurotransmitter release triggered independently of calcium influx. Journal of Physiology 542: 779-793. Paper in PDF format

Michel, F.J. & Trudeau, L.-E. (2000) Clozapine inhibits synaptic transmission at GABAergic synapses established by ventral tegmental area neurones in culture. Neuropharmacology 39: 1536-1543. Paper in PDF format

Trudeau, L.-E. (2000) Activation of ventral tegmental area astrocytes by
neurotensin: evidence for the involvement of multiple receptors Neuroscience97: 293-302.  Paper in PDF format

Bourque, M.-J. & Trudeau, L.-E. (2000) GDNF enhances the synaptic efficacy of dopaminergic neurons in culture. European Journal of Neuroscience 12:3172-3181. Paper in PDF format     (Éditeur: Blackwell Science/EJN)

Trudeau, L.-E., Parpura, V.P. & Haydon, P.G. (1999) Activation of neurotransmitter release in hippocampal nerve terminals during recovery from intracellular acidification. Journal of Neurophysiology 81: 2627-2635.  Paper in PDF format

Haydon, P.G. & Trudeau, L.-É. (1998) Regulatory roles for GTP-binding proteins in nerve terminals. Seminars in Neuroscience 9: 220-231.

Bahls, F.H., Lartius, R.K., Trudeau, L.-E., Doyle, R.T., Fang, Y., Witcher, D.R., Campbell, K.P. & Haydon, P.G. (1998) Contact dependent regulation of N-type calcium channel subunits during synaptogenesis. Journal ofNeurobiology35: 198-208.  Paper in PDF format

Trudeau, L.-É., Fang, Y. & Haydon, P.G. (1998) Modulation of an early step in the secretory machinery in hippocampal nerve terminals Proceedings of the National Academy of Sciences USA 95: 7163-7168.  Paper in PDF format

Trudeau, L.-É. , Doyle, R.T., Emery, D.G. & Haydon, P.G. (1996) Calcium-independent activation of the secretory apparatus by ruthenium red in hippocampal neurons: a new tool to assess modulation of presynaptic function. J.Neurosci. 16: 46-54. Paper in PDF format

Trudeau, L.-É., Emery, D.G., & Haydon, P.G. (1996) Direct modulation of the secretory machinery underlies PKA-dependent synaptic facilitation in hippocampal neurons. Neuron 17 :789-797.  Paper in PDF format